Nice! Glad you’re digging KDE. After Plasma 6 was released, there were internal discussions at Fedora about KDE becoming the new default DE. I’d have to think a lot of folks went through your experience, I know I did when starting with Fedora.

Marburg virus is no joke!! Fatality rate upwards of 88% due to it causing hemorrhagic fever. While monkey pox is no joke, I’d be exponentially more terrified if I had a Marburg virus infection.

You didn’t read the webpage, ah? While the site can pair folks up as an absolute last resort, this was designed for people to make the pact with a family member or friend. But if a person has no one whose word they can trust, the site is an option, yet the pact wasn’t exactly intended for them. But for everyone else, it’s a valid and amazing idea providing a breath of fresh air.

Third parties struggle to get on most ballots, as we’ve seen time and time again this year. Without being on enough ballots, they aren’t given time on the debate stage. Meaning they struggle to reach enough voters through alternative outlets to have any chance of making changes in this dire bipartisan landscape.

Removed by mod

Virulence is defined as causing damage to the host. If the virus kills everyone in that small proximity, the virus will no longer be able to reproduce or spread, plain and simple.

Viruses are super crafty in obtaining their limited number of proteins from the host. However, some viruses bring enzymes with them to get the job done without much help from the host. These are typically larger RNA viruses. Influenza is in this group, but it still steals the 5’ cap from the host. This happens without miss as it’s able to interact with the host RNA polymerase undetected and then this cap makes it so the influenza RNA appears to be host RNA.

The 1918 influenza was so deadly as it had just jumped to a new host, humans. The same exact influenza responsible for the 1918 pandemic has relatives still in circulation. It’s not in circulation as the less virulent versions were more successful. This explicitly demonstrates the preference to be less virulent.

If a virus doesn’t need many proteins from the host, it’s able to reproduce much more quickly than one dependant on more host resources. The more resources it needs, the increased ability of the immune system to prevent it’s reproduction. So in many situations, a lower requirement for host resources can make it more successful. Regardless, it can be very dependent on host resources, like many DNA viruses, and still not be very virulent. A great example of this is Hepatitis D. Virology is a fascinating field and it’s highly intricate as a virus is more like it’s host than any other viruses. There’s not a lot of commonality between different viruses and their reproduction cycles. So viruses in the same family are compared, and the 1918 becoming less virulent shows there’s a preference for becoming less virulent over time.

Then why does bird flu have more invasive symptoms and a higher mortality rate compared to human influenza’s? I was taught by a virologist who’s been around the block many times and got her PhD in the USSR. She was adamant that a parasite never wants to kill it’s host, as this results in no longer being able to reproduce in the host and shortens it’s reproduction time in future host.

Most viral offspring are not capable of infection, as without mutations, viruses would not be able to reproduce effectively and could not adapt to changing environments. To disprove a hypothesis simply means one aspect of the statement is incorrect. So while the cause and effect occurs, the explanation for why wasn’t dialed. Or at least, this would be my guess for how it could have been disproven.

We’ve known since at least March that about 10 human cases of this new bird flu would allow the virus to mutate and adapt to humans. This is the 14th reported case in the states this year, and the first which could have been transmitted from human to human. We understood what was happening, yet have really done nothing to try to prevent it’s spread.

The mutation rate baked into Influenza’s reproduction cycle is much more elaborate than coronaviruses, and this isn’t exactly a bad thing. When a human catches bird flu from a bird, the mortality rates are pretty burly as this version of the virus attaches to the α2:3 receptor. While this receptor is found throughout the avian digestive and respiratory track, it’s only found in the lower lungs of humans. A lower lung infection will always be gnarlier than an upper respiratory infection. Human influenza viruses have a preference for the α2:6 receptor, which is found throughout our airway. This is the primary adaptation which occurs when influenza mutates to infect humans. But a virus is a parasite, so in their ideal world, they wouldn’t kill their host. Viruses often do the most damage when adapting to or having recently adapted to a new host. Hopefully, the mutation rate of influenza will result in a shorter pandemic compared to COVID if it ends up taking place.

He’s truly phenomenal, basically the Harry Mack of spinning. Their set together is unreal!

https://yewtu.be/watch?v=ggLpFa6CQyU

Marc Rebillet and Thundercat had sets too, plus Hamilton Morris was going to give a lecture. The line up was pretty stacked overall and early bird tickets were $250, which isn’t unreasonable for a 3 day festival.

Android user? Graphene looks like it’s worth the setup process more and more. Pixels are the only Google product worth while thanks to Graphene really.

Just like the link in the iOS section, there’s a link in the Android section. Both were in the first sentence, I believe. But I had to give the article another once over to find it.

I mean, the doc’s are available through the link. But here’s some screen grabs:

AFU: After First Unlock

BFU: Before First Unlock

BF: Brute Force

FBE: File Based Encryption

FDE: Full Device Encryption

FFS: Full File System

They were arrested for a violent protest that resulted in setting fire to a construction site which was building temporary housing for asylum seekers. Seems pretty straight forward they were protesting the state helping those seeking asylum, no?

Well, only very specific viruses entry the nucleus, most often due to not bringing along enzymes needed for replication. Then, there’s transducing viruses and non-transducing viruses, of which only one will retain it’s genome in the host genome. Both occur near oncogenic gene locations too, which is why viral infections can lead to cancer, but this isn’t very common at all. IDK, guess I’ve always felt bacteria are way more complex and that it makes sense CRISPR comes from them. Bacterial viruses, aka bacteria phages, were the evolutionary pressure which lead to CRISPR’s development. But I’m a nerd and stay up to date with it all, so maybe that shifted my outlook.

Sorry for the delayed reply, but I studied in this field as welll, so curious why you thought CRISPR would be associated with viruses over bacteria or even mold/yeast?

Only portions of the code are published while the rest is kept under wraps. Classic corporate America bs finding a loop hole to use a trendy term.

Just to be clear, Gemma is only partially open sourced in select area’s of the code.

Ok, interesting, thanks for the correction. Do you think rephrasing my statement and stating Linus’s kernel is more adaptive would be more accurate?

It was revolutionary when it was first isolated from bacteria. Always fascinating to me that it’s pretty much the bacterial adaptive immune system. Now it’s awesome seeing other scientists dial in the precision of an already game changing advancement.

Stallman’s attempt to rename Linux to incorporate the GNU name not happening was frustrating on his end it seems. Everytime someone calls their system a Linux based OS and not GNU/Linux based OS downplays the work he put in. However, Linus’s kernel was more elaborate than GNU Hurd, so it was incorporated. It’s said Stallman is a visionary, while Linus is a programist. While there’s never been any display of tension in a back and forth between them online, it’s always seemed to me they appreciate and also despise various aspects of each another.