I just checked my AMD box and tailscale there can consume ~15% of cpu time when the tunnel is under active use. When it’s not used it’s ~1.5%. But it’s a low power old AMD cpu though (AMD G-T56N), so I’m not use if it compares to Ryzen 5. On my intel machine, it’s ~5% when under active use, and idle at ~0.5%.
uBlock Origin is already less effective when running in Chrome than in Firefox. For example, it can’t detect CNAME cloaking on Chrome, while it can do that in Firefox. When Chrome finally enforce manifest V3, uBlock Origin will be even more neutered in chrome due to limited number of blocking rules.